The LEOPARD Syndrome
Report:
Sinus tachycardia 122/min
Right axis deviation +150o
Right bundle branch block
Nonspecific ST/T changes
Lead V1 â V3 reversal
Comment:
There are multiple eponyms for this rare autosomal dominant syndrome but the acronym LEOPARD is the most commonly used name. It stands for lentigines, electrocardiographic conduction anomalies, ocular hypertelorism, pulmonic stenosis, abnormal genitals, retarded growth and deafness. There is nothing specific about the ECG abnormalities, commonly 1o AV block, LAHB and IVCD. Their significance is highly variable; sudden death has been reported.
Other cardiac involvement comprises pulmonary and sometimes aortic stenosis, fibroelastosis or HOCM. Overall cardiac involvement in the syndrome is present in 95% of cases.
This ECG could be interpreted as RBBB with LPHB if RVH can be excluded. Not enough is known at present to advise prophylactic pacing (or ICD). This patient had no other evidence of cardiac involvement and no relevant symptoms.
Reader, if the patient did not have the interesting LEOPARD syndrome, his ECG would not be in this Library.
Fig 64. 89 year old man with complex ECG but no cardiac history or symptoms.
If you have any suggestions for or feedback on this report, please let us know.
Hi, can we chat about some terms and conditions?
The library and its records are licensed under the Creative Commons Attribution 4.0 International license.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
By clicking agree below, you are agreeing to adhere to CC BY 4.0.